Down-Regulation of Gli Transcription Factor Leads to the Inhibition of Migration and Invasion of Ovarian Cancer Cells via Integrin β4-Mediated FAK Signaling

BACKGROUND: Recent evidence suggests that aberrant activation of Hedgehog (Hh) signaling by Gli transcription factors is characteristic of a variety of aggressive human carcinomas including ovarian cancer. Therefore, chemotherapeutic agents that inhibit activation of Gli transcription factors have e...

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Detalles Bibliográficos
Autores principales: Chen, Qi, Xu, Rong, Zeng, Chunyan, Lu, Quqin, Huang, Dengliang, Shi, Chao, Zhang, Weilong, Deng, Libin, Yan, Runwei, Rao, Hai, Gao, Guolan, Luo, Shiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922814/
https://www.ncbi.nlm.nih.gov/pubmed/24533083
http://dx.doi.org/10.1371/journal.pone.0088386

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