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Tertiary structure prediction and identification of druggable pocket in the cancer biomarker – Osteopontin-c
BACKGROUND: Osteopontin (Eta, secreted sialoprotein 1, opn) is secreted from different cell types including cancer cells. Three splice variant forms namely osteopontin-a, osteopontin-b and osteopontin-c have been identified. The main astonishing feature is that osteopontin-c is found to be elevated...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922830/ https://www.ncbi.nlm.nih.gov/pubmed/24401206 http://dx.doi.org/10.1186/2251-6581-13-13 |