Cargando…

Proteomic screening of molecular targets of crocin

BACKGROUND: Traditional drug discovery approaches are mainly relied on the observed phenotypic changes following administration of a plant extract, drug candidate or natural product. Recently, target-based approaches are becoming more popular. The present study aimed to identify the cellular targets...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hosseinzadeh, Hossein, Mehri, Soghra, Heshmati, Ali, Ramezani, Mohammad, Sahebkar, Amirhossein, Abnous, Khalil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922837/ https://www.ncbi.nlm.nih.gov/pubmed/24393168 http://dx.doi.org/10.1186/2008-2231-22-5

Ejemplares similares

Affinity-based target deconvolution of safranal
por: Hosseinzadeh, Hossein, et al.
Publicado: (2013)

Crocin reduced acrylamide-induced neurotoxicity in Wistar rat through inhibition of oxidative stress
por: Mehri, Soghra, et al.
Publicado: (2015)

Antidepressant effects of crocin and its effects on transcript and protein levels of CREB, BDNF, and VGF in rat hippocampus
por: Vahdati Hassani, Faezeh, et al.
Publicado: (2014)

The effects of crocin on spatial memory impairment induced by hyoscine: Role of NMDA, AMPA, ERK, and CaMKII proteins in rat hippocampus
por: Adabizadeh, Maliheh, et al.
Publicado: (2019)

Protective effect of crocin on bisphenol A - induced spatial learning and memory impairment in adult male rats: Role of oxidative stress and AMPA receptor
por: Vahdati Hassani, Faezeh, et al.
Publicado: (2020)

Memory enhancement and protective effects of crocin against D-galactose aging model in the hippocampus of Wistar rats
por: Heidari, Somaye, et al.
Publicado: (2017)

Protective effect of crocin against d-galactose-induced aging in mice
por: Mohammadi, Elaheh, et al.
Publicado: (2018)

Crocin Restores Hypotensive Effect of Subchronic Administration of Diazinon in Rats
por: Razavi, Marjan, et al.
Publicado: (2013)

Protective Effects of Crocin Against Hepatic Damages in D-galactose Aging Model in Rats
por: Omidkhoda, Seyedeh Farzaneh, et al.
Publicado: (2020)

The Prophylactic and Therapeutic Effects of Saffron Extract and Crocin on Ethanol Withdrawal Syndrome in Mice
por: Shoja, Maryam, et al.
Publicado: (2018)

Protective Effect of Crocin against Mitochondrial Damage and Memory Deficit Induced by Beta-amyloid in the Hippocampus of Rats
por: Yousefsani, Bahareh Sadat, et al.
Publicado: (2021)

Crocin Prevents Sub-Cellular Organelle Damage, Proteolysis and Apoptosis in Rat Hepatocytes: A Justification for Its Hepatoprotection
por: Yousefsani, Bahareh Sadat, et al.
Publicado: (2018)

Protective Effect of Crocin on Malathion-induced Cardiotoxicity in Rats: A Biochemical, Histopathological and Proteomics Study
por: Balarastaghi, Soudabeh, et al.
Publicado: (2021)

Crocin prevents haloperidol-induced orofacial dyskinesia: possible an antioxidant mechanism
por: Kamyar, Marzyeh, et al.
Publicado: (2016)

Study of the Role of CREB, BDNF, and VGF Neuropeptide in Long Term Antidepressant Activity of Crocin in the Rat Cerebellum
por: Razavi, Bibi Marjan, et al.
Publicado: (2017)

Preventive effects of crocin on neuronal damages induced by D-galactose through AGEs and oxidative stress in human neuroblastoma cells (SH-SY5Y)
por: Heidari, Somaye, et al.
Publicado: (2018)

Involvement of brain-derived neurotrophic factor (BDNF) on malathion induced depressive-like behavior in subacute exposure and protective effects of crocin
por: Dorri, Somaye Ardebili, et al.
Publicado: (2015)

Effect of Topiramate on Morphine-induced Conditioned Place Preference (CPP) in Rats: Role of ERK and CREB Proteins in Hippocampus and Cerebral Cortex
por: Bagherpasand, Nima, et al.
Publicado: (2019)

Screening and identification of SUMP-proteins in sub-acute treatment with diazinon
por: Yazdian-Robati, Rezvan, et al.
Publicado: (2015)

Crocin Improves Oxidative Stress by Potentiating Intrinsic Anti-Oxidant Defense Systems in Pancreatic Cells During Uncontrolled Hyperglycemia
por: Yaribeygi, Habib, et al.
Publicado: (2019)

In vitro evaluation of dihydropyridine-3-carbonitriles as potential cytotoxic agents through PIM-1 protein kinase inhibition
por: Abnous, Khalil, et al.
Publicado: (2017)

Synthesis and molecular modeling of six novel monastrol analogues: evaluation of cytotoxicity and kinesin inhibitory activity against HeLa cell line
por: Abnous, Khalil, et al.
Publicado: (2013)

Safety Evaluation of Crocin (a constituent of saffron) Tablets in Healthy Volunteers
por: Mohamadpour, Amir Houshang, et al.
Publicado: (2013)

Comparison of pharmacokinetic parameters of ranolazine between diabetic and non-diabetic rats
por: Mashayekhi-sardoo, Habibeh, et al.
Publicado: (2022)

Application of Nanoliposomes Containing Nisin and Crocin in Milk
por: Yousefi, Mohammad, et al.
Publicado: (2023)

The effects of Crataegus pinnatifida (Chinese hawthorn) on metabolic syndrome: A review
por: Dehghani, Shahrzad, et al.
Publicado: (2019)

Berberis vulgaris and its constituent berberine as antidotes and protective agents against natural or chemical toxicities
por: Mohammadzadeh, Nooshin, et al.
Publicado: (2017)

A review of the effects of Urtica dioica (nettle) in metabolic syndrome
por: Samakar, Bahareh, et al.
Publicado: (2022)

Ceftriaxone, a Beta-Lactam Antibiotic, Modulates Apoptosis Pathways and Oxidative Stress in a Rat Model of Neuropathic Pain
por: Amin, Bahareh, et al.
Publicado: (2014)

Evaluation of the antidepressant-like effects of acute and sub-acute administration of crocin and crocetin in mice
por: Amin, Bahareh, et al.
Publicado: (2015)

Effects of chronic crocin treatment on desoxycorticosterone acetate (doca)-salt hypertensive rats
por: Imenshahidi, Mohsen, et al.
Publicado: (2014)

Toxicology effects of saffron and its constituents: a review
por: Bostan, Hasan Badie, et al.
Publicado: (2017)

Anti-Aging Effect of Nigella Sativa Fixed Oil on D-Galactose-Induced Aging in Mice
por: Shahroudi, Mahdieh Jafari, et al.
Publicado: (2017)

Crocus Sativus L. (Saffron) Extract and its Active Constituents (Crocin and Safranal) on Ischemia-Reperfusion in Rat Skeletal Muscle
por: Hosseinzadeh, Hossein, et al.
Publicado: (2009)

Cardioprotective Effect of Saffron Extract and Safranal in Isoproterenol-Induced Myocardial Infarction in Wistar Rats
por: Mehdizadeh, Roya, et al.
Publicado: (2013)

Evaluation of possible effects of crocin against nitrate tolerance and endothelial dysfunction
por: Omidkhoda, Seyedeh Farzaneh, et al.
Publicado: (2020)

Crocin Effects on Human Myeloma Cells Regarding Intracellular Redox State, DNA Fragmentation, and Apoptosis or Necrosis Profile
por: Rezaee, Ramin, et al.
Publicado: (2014)

Synthesis of doxorubicin-loaded peptosomes hybridized with gold nanorod for targeted drug delivery and CT imaging of metastatic breast cancer
por: Hasannia, Maliheh, et al.
Publicado: (2022)

Alkyl cross-linked low molecular weight polypropyleneimine dendrimers as efficient gene delivery vectors
por: Ariaee, Faezeh Moghadam, et al.
Publicado: (2016)

Effect of crocin, an active saffron constituent, on ethanol toxicity in the rat: histopathological and biochemical studies
por: Rezaee-Khorasany, Alireza, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_tketj6qn4vvuuaqtg3darocgpv