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DNA-dependent protein kinase catalytic subunit (DNA-PKcs)-SIN1 association mediates ultraviolet B (UVB)-induced Akt Ser-473 phosphorylation and skin cell survival

BACKGROUND: The exposure of skin keratinocytes to Ultraviolet (UV) irradiation leads to Akt phosphorylation at Ser-473, which is important for the carcinogenic effects of excessive sun exposure. The present study investigated the underlying mechanism of Akt Ser-473 phosphorylation by UVB radiation....

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Detalles Bibliográficos
Autores principales:	Tu, Ying, Ji, Chao, Yang, Bo, Yang, Zhi, Gu, Hua, Lu, Chun-Cheng, Wang, Rong, Su, Zhong-Lan, Chen, Bin, Sun, Wei-Ling, Xia, Ji-Ping, Bi, Zhi-Gang, He, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922905/ https://www.ncbi.nlm.nih.gov/pubmed/24365180 http://dx.doi.org/10.1186/1476-4598-12-172

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