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CMV Latent Infection Improves CD8+ T Response to SEB Due to Expansion of Polyfunctional CD57+ Cells in Young Individuals
Cytomegalovirus (CMV) latent infection has a deleterious effect on the efficacy of influenza vaccination in the elderly, suggesting that CMV restricts immunological diversity impairing the immune system functionality in old age. Polyfunctional T cells produce multiple cytokines and higher amounts th...
Autores principales: | Pera, Alejandra, Campos, Carmen, Corona, Alonso, Sanchez-Correa, Beatriz, Tarazona, Raquel, Larbi, Anis, Solana, Rafael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922920/ https://www.ncbi.nlm.nih.gov/pubmed/24533103 http://dx.doi.org/10.1371/journal.pone.0088538 |
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