The SFT-1 and OXA-1 respiratory chain complex assembly factors influence lifespan by distinct mechanisms in C. elegans

BACKGROUND: C. elegans mitochondrial (Mit) mutants have disrupted mitochondrial electron transport chain function, yet, surprisingly, they are often long-lived, a property that has offered unique insights into the molecular mechanisms of aging. In this study, we examine the phenotypic consequences o...

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Detalles Bibliográficos
Autores principales: Maxwell, Sara, Harding, Joanne, Brabin, Charles, Appleford, Peter J, Brown, Ruth, Delaney, Carol, Brown, Garry, Woollard, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922957/
https://www.ncbi.nlm.nih.gov/pubmed/24472117
http://dx.doi.org/10.1186/2046-2395-2-9

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