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NMR structure of the 5′ splice site in the group IIB intron Sc.ai5γ—conformational requirements for exon–intron recognition

A crucial step of the self-splicing reaction of group II intron ribozymes is the recognition of the 5′ exon by the intron. This recognition is achieved by two regions in domain 1 of the intron, the exon-binding sites EBS1 and EBS2 forming base pairs with the intron-binding sites IBS1 and IBS2 locate...

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Detalles Bibliográficos
Autores principales: Kruschel, Daniela, Skilandat, Miriam, Sigel, Roland K.O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923125/
https://www.ncbi.nlm.nih.gov/pubmed/24448450
http://dx.doi.org/10.1261/rna.041137.113

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