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Molecular crowders and cosolutes promote folding cooperativity of RNA under physiological ionic conditions
Folding mechanisms of functional RNAs under idealized in vitro conditions of dilute solution and high ionic strength have been well studied. Comparatively little is known, however, about mechanisms for folding of RNA in vivo where Mg(2+) ion concentrations are low, K(+) concentrations are modest, an...
Autores principales: | Strulson, Christopher A., Boyer, Joshua A., Whitman, Elisabeth E., Bevilacqua, Philip C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923128/ https://www.ncbi.nlm.nih.gov/pubmed/24442612 http://dx.doi.org/10.1261/rna.042747.113 |
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