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Molecular crowders and cosolutes promote folding cooperativity of RNA under physiological ionic conditions

Folding mechanisms of functional RNAs under idealized in vitro conditions of dilute solution and high ionic strength have been well studied. Comparatively little is known, however, about mechanisms for folding of RNA in vivo where Mg(2+) ion concentrations are low, K(+) concentrations are modest, an...

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Detalles Bibliográficos
Autores principales: Strulson, Christopher A., Boyer, Joshua A., Whitman, Elisabeth E., Bevilacqua, Philip C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923128/
https://www.ncbi.nlm.nih.gov/pubmed/24442612
http://dx.doi.org/10.1261/rna.042747.113

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