Improved design of hammerhead ribozyme for selective digestion of target RNA through recognition of site-specific adenosine-to-inosine RNA editing

Adenosine-to-inosine (A-to-I) RNA editing is an endogenous regulatory mechanism involved in various biological processes. Site-specific, editing-state–dependent degradation of target RNA may be a powerful tool both for analyzing the mechanism of RNA editing and for regulating biological processes. P...

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Detalles Bibliográficos
Autores principales: Fukuda, Masatora, Kurihara, Kei, Yamaguchi, Shota, Oyama, Yui, Deshimaru, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923133/
https://www.ncbi.nlm.nih.gov/pubmed/24448449
http://dx.doi.org/10.1261/rna.041202.113

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