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Neuron-specific regulation of class I PI3K catalytic subunits and their dysfunction in brain disorders
The phosphoinositide 3-kinase (PI3K) complex plays important roles in virtually all cells of the body. The enzymatic activity of PI3K to phosphorylate phosphoinositides in the membrane is mediated by a group of catalytic and regulatory subunits. Among those, the class I catalytic subunits, p110α, p1...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923137/ https://www.ncbi.nlm.nih.gov/pubmed/24592210 http://dx.doi.org/10.3389/fnmol.2014.00012 |