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Classical and Paradoxical Effects of TNF-α on Bone Homeostasis

Tumor necrosis factor-α (TNF-α) plays an essential role in the regulation of bone homeostasis in several chronic immune and inflammatory joint diseases, where inhibition of TNF has led to significant clinical improvement. However, TNF-activated pathways and mechanisms involved in bone remodeling rem...

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Detalles Bibliográficos
Autores principales:	Osta, Bilal, Benedetti, Giulia, Miossec, Pierre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923157/ https://www.ncbi.nlm.nih.gov/pubmed/24592264 http://dx.doi.org/10.3389/fimmu.2014.00048

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