An abundant dysfunctional apolipoprotein A1 in human atheroma

Recent studies indicate high density lipoproteins (HDL) and their major structural protein, apolipoprotein A1 (apoA1), recovered from human atheroma, are dysfunctional and extensively oxidized by myeloperoxidase (MPO), while in vitro oxidation of apoA1/HDL by MPO impairs its cholesterol acceptor fun...

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Detalles Bibliográficos
Autores principales: Huang, Ying, DiDonato, Joseph A., Levison, Bruce S., Schmitt, Dave, Li, Lin, Wu, Yuping, Buffa, Jennifer, Kim, Timothy, Gerstenecker, Gary, Gu, Xiaodong, Kadiyala, Chandra, Wang, Zeneng, Culley, Miranda K., Hazen, Jennie E., DiDonato, Anthony J., Fu, Xiaoming, Berisha, Stela, Peng, Daoquan, Nguyen, Truc, Liang, Shaohong, Chuang, Chia-Chi, Cho, Leslie, Plow, Edward F., Fox, Paul L., Gogonea, Valentin, Tang, W.H. Wilson, Parks, John S., Fisher, Edward A., Smith, Jonathan D., Hazen, Stanley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923163/
https://www.ncbi.nlm.nih.gov/pubmed/24464187
http://dx.doi.org/10.1038/nm.3459

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