Surface Plasmon Spectroscopic Detection of Saxitoxin

For the surface-optoelectronic study of Saxitoxin sensing, we fabricated self-assembled calix[4]arene derivative monolayers as the recognition-functional interfaces on a gold surface. An interaction study between Saxitoxin and calix[4]arene derivative monolayers were performed using surface plasmon...

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Detalles Bibliográficos
Autores principales: Chen, Hongxia, Kim, Youn Sook, Keum, Sam-Rok, Kim, Sung-Hoon, Choi, Heung-Jin, Lee, Jaebeom, An, Won Gun, Koh, Kwangnak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2007
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923172/
Descripción
Sumario:For the surface-optoelectronic study of Saxitoxin sensing, we fabricated self-assembled calix[4]arene derivative monolayers as the recognition-functional interfaces on a gold surface. An interaction study between Saxitoxin and calix[4]arene derivative monolayers were performed using surface plasmon resonance (SPR) spectroscopy. Among three calix[4]arene derivatives, calix[4]arene crown ether SAM showed the highest sensitivity to Saxitoxin. The detection limit of this system is three orders of magnitude lower than that of the mouse bioassay which is the current benchmark for Saxitoxin detection.

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