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Wnt Secretion from Epithelial Cells and Subepithelial Myofibroblasts Is Not Required in the Mouse Intestinal Stem Cell Niche In Vivo

Wnt signaling is a crucial aspect of the intestinal stem cell niche required for crypt cell proliferation and differentiation. Paneth cells or subepithelial myofibroblasts are leading candidate sources of the required Wnt ligands, but this has not been tested in vivo. To abolish Wnt-ligand secretion...

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Detalles Bibliográficos
Autores principales:	San Roman, Adrianna K., Jayewickreme, Chenura D., Murtaugh, L. Charles, Shivdasani, Ramesh A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923227/ https://www.ncbi.nlm.nih.gov/pubmed/24527386 http://dx.doi.org/10.1016/j.stemcr.2013.12.012

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