DeNovoGUI: An Open Source Graphical User Interface for de Novo Sequencing of Tandem Mass Spectra

[Image: see text] De novo sequencing is a popular technique in proteomics for identifying peptides from tandem mass spectra without having to rely on a protein sequence database. Despite the strong potential of de novo sequencing algorithms, their adoption threshold remains quite high. We here prese...

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Detalles Bibliográficos
Autores principales: Muth, Thilo, Weilnböck, Lisa, Rapp, Erdmann, Huber, Christian G., Martens, Lennart, Vaudel, Marc, Barsnes, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923451/
https://www.ncbi.nlm.nih.gov/pubmed/24295440
http://dx.doi.org/10.1021/pr4008078
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author Muth, Thilo
Weilnböck, Lisa
Rapp, Erdmann
Huber, Christian G.
Martens, Lennart
Vaudel, Marc
Barsnes, Harald
author_facet Muth, Thilo
Weilnböck, Lisa
Rapp, Erdmann
Huber, Christian G.
Martens, Lennart
Vaudel, Marc
Barsnes, Harald
author_sort Muth, Thilo
collection PubMed
description [Image: see text] De novo sequencing is a popular technique in proteomics for identifying peptides from tandem mass spectra without having to rely on a protein sequence database. Despite the strong potential of de novo sequencing algorithms, their adoption threshold remains quite high. We here present a user-friendly and lightweight graphical user interface called DeNovoGUI for running parallelized versions of the freely available de novo sequencing software PepNovo+, greatly simplifying the use of de novo sequencing in proteomics. Our platform-independent software is freely available under the permissible Apache2 open source license. Source code, binaries, and additional documentation are available at http://denovogui.googlecode.com.
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spelling pubmed-39234512014-02-13 DeNovoGUI: An Open Source Graphical User Interface for de Novo Sequencing of Tandem Mass Spectra Muth, Thilo Weilnböck, Lisa Rapp, Erdmann Huber, Christian G. Martens, Lennart Vaudel, Marc Barsnes, Harald J Proteome Res [Image: see text] De novo sequencing is a popular technique in proteomics for identifying peptides from tandem mass spectra without having to rely on a protein sequence database. Despite the strong potential of de novo sequencing algorithms, their adoption threshold remains quite high. We here present a user-friendly and lightweight graphical user interface called DeNovoGUI for running parallelized versions of the freely available de novo sequencing software PepNovo+, greatly simplifying the use of de novo sequencing in proteomics. Our platform-independent software is freely available under the permissible Apache2 open source license. Source code, binaries, and additional documentation are available at http://denovogui.googlecode.com. American Chemical Society 2013-12-02 2014-02-07 /pmc/articles/PMC3923451/ /pubmed/24295440 http://dx.doi.org/10.1021/pr4008078 Text en Copyright © 2013 American Chemical Society Terms of Use (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html)
spellingShingle Muth, Thilo
Weilnböck, Lisa
Rapp, Erdmann
Huber, Christian G.
Martens, Lennart
Vaudel, Marc
Barsnes, Harald
DeNovoGUI: An Open Source Graphical User Interface for de Novo Sequencing of Tandem Mass Spectra
title DeNovoGUI: An Open Source Graphical User Interface for de Novo Sequencing of Tandem Mass Spectra
title_full DeNovoGUI: An Open Source Graphical User Interface for de Novo Sequencing of Tandem Mass Spectra
title_fullStr DeNovoGUI: An Open Source Graphical User Interface for de Novo Sequencing of Tandem Mass Spectra
title_full_unstemmed DeNovoGUI: An Open Source Graphical User Interface for de Novo Sequencing of Tandem Mass Spectra
title_short DeNovoGUI: An Open Source Graphical User Interface for de Novo Sequencing of Tandem Mass Spectra
title_sort denovogui: an open source graphical user interface for de novo sequencing of tandem mass spectra
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923451/
https://www.ncbi.nlm.nih.gov/pubmed/24295440
http://dx.doi.org/10.1021/pr4008078
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