Cloud-based simulations on Google Exacycle reveal ligand-modulation of GPCR activation pathways

Simulations can provide tremendous insight into atomistic details of biological mechanisms, but micro- to milliseconds timescales are historically only accessible on dedicated supercomputers. We demonstrate that cloud computing is a viable alternative, bringing long-timescale processes within reach...

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Detalles Bibliográficos
Autores principales: Kohlhoff, Kai J., Shukla, Diwakar, Lawrenz, Morgan, Bowman, Gregory R., Konerding, David E., Belov, Dan, Altman, Russ B., Pande, Vijay S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923464/
https://www.ncbi.nlm.nih.gov/pubmed/24345941
http://dx.doi.org/10.1038/nchem.1821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923464/
https://www.ncbi.nlm.nih.gov/pubmed/24345941
http://dx.doi.org/10.1038/nchem.1821

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