Dichloroacetate modulates cytokines toward T helper 1 function via induction of the interleukin-12–interferon-γ pathway

BACKGROUND: Dichloroacetate (DCA) is one of the new, promising anticancer drugs. DCA restores normal mitochondrial function and enables cancer cells to undergo apoptosis. In addition, DCA was found to modulate certain signaling pathways involving some transcription factors. The latter encouraged us...

Descripción completa

Detalles Bibliográficos
Autores principales: Badr, Mujtaba M, Qinna, Nidal A, Qadan, Fadi, Matalka, Khalid Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923616/
https://www.ncbi.nlm.nih.gov/pubmed/24532971
http://dx.doi.org/10.2147/OTT.S56688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923616/
https://www.ncbi.nlm.nih.gov/pubmed/24532971
http://dx.doi.org/10.2147/OTT.S56688

Ejemplares similares