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Deficiency of the BiP cochaperone ERdj4 causes constitutive endoplasmic reticulum stress and metabolic defects

Endoplasmic reticulum–localized DnaJ 4 (ERdj4) is an immunoglobulin-binding protein (BiP) cochaperone and component of the endoplasmic reticulum–associated degradation (ERAD) pathway that functions to remove unfolded/misfolded substrates from the ER lumen under conditions of ER stress. To elucidate...

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Detalles Bibliográficos
Autores principales:	Fritz, Jill M., Dong, Mei, Apsley, Karen S., Martin, Emily P., Na, Cheng-Lun, Sitaraman, Sneha, Weaver, Timothy E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923636/ https://www.ncbi.nlm.nih.gov/pubmed/24336520 http://dx.doi.org/10.1091/mbc.E13-06-0319

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