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SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements
Apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional protein contributing to genome stability via repair of DNA lesions via the base excision repair pathway. It also plays a role in gene expression regulation and RNA metabolism. Another, poorly characterized function is its ability to bi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923644/ https://www.ncbi.nlm.nih.gov/pubmed/24356447 http://dx.doi.org/10.1091/mbc.E13-05-0286 |