Cargando…

SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements

Apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional protein contributing to genome stability via repair of DNA lesions via the base excision repair pathway. It also plays a role in gene expression regulation and RNA metabolism. Another, poorly characterized function is its ability to bi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Antoniali, Giulia, Lirussi, Lisa, D'Ambrosio, Chiara, Dal Piaz, Fabrizio, Vascotto, Carlo, Casarano, Elena, Marasco, Daniela, Scaloni, Andrea, Fogolari, Federico, Tell, Gianluca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923644/ https://www.ncbi.nlm.nih.gov/pubmed/24356447 http://dx.doi.org/10.1091/mbc.E13-05-0286

Ejemplares similares

Nucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells
por: Lirussi, Lisa, et al.
Publicado: (2012)

APE1 polymorphic variants cause persistent genomic stress and affect cancer cell proliferation
por: Lirussi, Lisa, et al.
Publicado: (2016)

Cleavage of the APE1 N-Terminal Domain in Acute Myeloid Leukemia Cells Is Associated with Proteasomal Activity
por: Lirussi, Lisa, et al.
Publicado: (2020)

Architecture of The Human Ape1 Interactome Defines Novel Cancers Signatures
por: Ayyildiz, Dilara, et al.
Publicado: (2020)

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism
por: Antoniali, Giulia, et al.
Publicado: (2017)

Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions
por: Fantini, Damiano, et al.
Publicado: (2010)

Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and function
por: Vascotto, Carlo, et al.
Publicado: (2011)

Mitochondrial translocation of APE1 relies on the MIA pathway
por: Barchiesi, Arianna, et al.
Publicado: (2015)

Revisiting Two Decades of Research Focused on Targeting APE1 for Cancer Therapy: The Pros and Cons
por: Malfatti, Matilde Clarissa, et al.
Publicado: (2023)

Impairment of enzymatic antioxidant defenses is associated with bilirubin-induced neuronal cell death in the cerebellum of Ugt1 KO mice
por: Bortolussi, G, et al.
Publicado: (2015)

Serum AP-endonuclease 1 (sAPE1) as novel biomarker for hepatocellular carcinoma
por: Pascut, Devis, et al.
Publicado: (2019)

Abasic and oxidized ribonucleotides embedded in DNA are processed by human APE1 and not by RNase H2
por: Malfatti, Matilde Clarissa, et al.
Publicado: (2017)

APE1 controls DICER1 expression in NSCLC through miR-33a and miR-130b
por: Antoniali, Giulia, et al.
Publicado: (2022)

Transcriptional Up-Regulation of APE1/Ref-1 in Hepatic Tumor: Role in Hepatocytes Resistance to Oxidative Stress and Apoptosis
por: Di Maso, Vittorio, et al.
Publicado: (2015)

Specific Inhibition of the Redox Activity of Ape1/Ref-1 by E3330 Blocks Tnf-Α-Induced Activation of Il-8 Production in Liver Cancer Cell Lines
por: Cesaratto, Laura, et al.
Publicado: (2013)

SIRT1 deacetylates APE1 and regulates cellular base excision repair
por: Yamamori, Tohru, et al.
Publicado: (2010)

Correction: Specific Inhibition of the Redox Activity of Ape1/Ref-1 by E3330 Blocks Tnf-Α-Induced Activation of Il-8 Production in Liver Cancer Cell Lines
por: Cesaratto, Laura, et al.
Publicado: (2013)

Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia
por: Scognamiglio, Pasqualina Liana, et al.
Publicado: (2016)

The Redox Function of APE1 Is Involved in the Differentiation Process of Stem Cells toward a Neuronal Cell Fate
por: Domenis, Rossana, et al.
Publicado: (2014)

SIRT1/APE1 promotes the viability of gastric cancer cells by inhibiting p53 to suppress ferroptosis
por: Zhao, Huijin, et al.
Publicado: (2023)

Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP
por: Pines, Alex, et al.
Publicado: (2005)

From APE to APE-100: present and future of the APE project
por: Bacilieri, P, et al.
Publicado: (1988)

SIRT6 protein deacetylase interacts with MYH DNA glycosylase, APE1 endonuclease, and Rad9–Rad1–Hus1 checkpoint clamp
por: Hwang, Bor-Jang, et al.
Publicado: (2015)

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination
por: Guikema, Jeroen E.J., et al.
Publicado: (2007)

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination
por: Guikema, Jeroen E.J., et al.
Publicado: (2007)

CHFR negatively regulates SIRT1 activity upon oxidative stress
por: Kim, Myungjin, et al.
Publicado: (2016)

The APE-100 computer; 1, the architecture
por: Battista, C, et al.
Publicado: (1993)

An APE1 inhibitor reveals critical roles of the redox function of APE1 in KSHV replication and pathogenic phenotypes
por: Zhong, Canrong, et al.
Publicado: (2017)

Knockout and Inhibition of Ape1: Roles of Ape1 in Base Excision DNA Repair and Modulation of Gene Expression
por: Xue, Zhouyiyuan, et al.
Publicado: (2022)

Apes
por: Lowenstine, Linda J., et al.
Publicado: (2018)

APE1 and NPM1 protect cancer cells from platinum compounds cytotoxicity and their expression pattern has a prognostic value in TNBC
por: Malfatti, Matilde Clarissa, et al.
Publicado: (2019)

APE1 promotes non-homologous end joining by initiating DNA double-strand break formation and decreasing ubiquitination of artemis following oxidative genotoxic stress
por: Zhang, Qin, et al.
Publicado: (2023)

Development of APE1 enzymatic DNA repair assays: low APE1 activity is associated with increase lung cancer risk
por: Sevilya, Ziv, et al.
Publicado: (2015)

Man-Apes or Ape-Men? The Story of Discoveries in Africa
por: Gardner, William U.
Publicado: (1967)

Phosphorylation and ubiquitination-dependent degradation of CABIN1 releases p53 for transactivation upon genotoxic stress
por: Choi, Soo-Youn, et al.
Publicado: (2013)

Heme detoxification by heme oxygenase-1 reinstates proliferative and immune balances upon genotoxic tissue injury
por: Hedblom, Andreas, et al.
Publicado: (2019)

APE1/Ref-1 Role in Inflammation and Immune Response
por: Oliveira, Thais Teixeira, et al.
Publicado: (2022)

Nucleophosmin modulates stability, activity, and nucleolar accumulation of base excision repair proteins
por: Poletto, Mattia, et al.
Publicado: (2014)

The mentality of apes
por: Köhler, Wolfgang, 1887-1967
Publicado: (1959)

The naked ape
por: Morris, Desmond
Publicado: (1967)

Cannot write session to /tmp/vufind_sessions/sess_1fskop0f6plu0me1j6ebua73kq