A BMP-FGF Morphogen Toggle Switch Drives the Ultrasensitive Expression of Multiple Genes in the Developing Forebrain

Borders are important as they demarcate developing tissue into distinct functional units. A key challenge is the discovery of mechanisms that can convert morphogen gradients into tissue borders. While mechanisms that produce ultrasensitive cellular responses provide a solution, how extracellular mor...

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Detalles Bibliográficos
Autores principales: Srinivasan, Shyam, Hu, Jia Sheng, Currle, D. Spencer, Fung, Ernest S., Hayes, Wayne B., Lander, Arthur D., Monuki, Edwin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923663/
https://www.ncbi.nlm.nih.gov/pubmed/24550718
http://dx.doi.org/10.1371/journal.pcbi.1003463

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