DNA Sequence Explains Seemingly Disordered Methylation Levels in Partially Methylated Domains of Mammalian Genomes

For the most part metazoan genomes are highly methylated and harbor only small regions with low or absent methylation. In contrast, partially methylated domains (PMDs), recently discovered in a variety of cell lines and tissues, do not fit this paradigm as they show partial methylation for large por...

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Detalles Bibliográficos
Autores principales: Gaidatzis, Dimos, Burger, Lukas, Murr, Rabih, Lerch, Anita, Dessus-Babus, Sophie, Schübeler, Dirk, Stadler, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923675/
https://www.ncbi.nlm.nih.gov/pubmed/24550741
http://dx.doi.org/10.1371/journal.pgen.1004143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923675/
https://www.ncbi.nlm.nih.gov/pubmed/24550741
http://dx.doi.org/10.1371/journal.pgen.1004143

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