Cargando…

The Centriolar Satellite Protein AZI1 Interacts with BBS4 and Regulates Ciliary Trafficking of the BBSome

Bardet-Biedl syndrome (BBS) is a well-known ciliopathy with mutations reported in 18 different genes. Most of the protein products of the BBS genes localize at or near the primary cilium and the centrosome. Near the centrosome, BBS proteins interact with centriolar satellite proteins, and the BBSome...

Descripción completa

Detalles Bibliográficos
Autores principales: Chamling, Xitiz, Seo, Seongjin, Searby, Charles C., Kim, GunHee, Slusarski, Diane C., Sheffield, Val C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923683/
https://www.ncbi.nlm.nih.gov/pubmed/24550735
http://dx.doi.org/10.1371/journal.pgen.1004083