Translation of TRO40303 from myocardial infarction models to demonstration of safety and tolerance in a randomized Phase I trial

BACKGROUND: Although reperfusion injury has been shown to be responsible for cardiomyocytes death after an acute myocardial infarction, there is currently no drug on the market that reduces this type of injury. TRO40303 is a new cardioprotective compound that was shown to inhibit the opening of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Le Lamer, Sophie, Paradis, Stéphanie, Rahmouni, Hidayat, Chaimbault, Corinne, Michaud, Magali, Culcasi, Marcel, Afxantidis, Jean, Latreille, Mathilde, Berna, Patrick, Berdeaux, Alain, Pietri, Sylvia, Morin, Didier, Donazzolo, Yves, Abitbol, Jean-Louis, Pruss, Rebacca M, Schaller, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923730/
https://www.ncbi.nlm.nih.gov/pubmed/24507657
http://dx.doi.org/10.1186/1479-5876-12-38

Ejemplares similares

Ejemplares similares