High Avidity CD8(+) T Cells Efficiently Eliminate Motile HIV-Infected Targets and Execute a Locally Focused Program of Anti-Viral Function

The dissemination of HIV from an initial site of infection is facilitated by motile HIV-infected CD4(+) T-cells. However, the impact of infected target cell migration on antigen recognition by HIV-specific CD8(+) T-cells is unclear. Using a 3D in vitro model of tissue, we visualized dynamic interact...

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Detalles Bibliográficos
Autores principales: Foley, Maria Hottelet, Forcier, Talitha, McAndrew, Elizabeth, Gonzalez, Michael, Chen, Huabiao, Juelg, Boris, Walker, Bruce D., Irvine, Darrell J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923750/
https://www.ncbi.nlm.nih.gov/pubmed/24551068
http://dx.doi.org/10.1371/journal.pone.0087873

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