A Fluorescence-Coupled Assay for Gamma Aminobutyric Acid (GABA) Reveals Metabolic Stress-Induced Modulation of GABA Content in Neuroendocrine Cancer

Pathways involved in the synthesis of the neurotransmitter gamma-aminobutyric acid (GABA) have been implicated in the pathogenesis of high grade neuroendocrine (NE) neoplasms as well as neoplasms from a non-NE lineage. Using The Cancer Genome Atlas, overexpression of the GABA synthetic enzyme, gluta...

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Detalles Bibliográficos
Autores principales: Ippolito, Joseph E., Piwnica-Worms, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923810/
https://www.ncbi.nlm.nih.gov/pubmed/24551133
http://dx.doi.org/10.1371/journal.pone.0088667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923810/
https://www.ncbi.nlm.nih.gov/pubmed/24551133
http://dx.doi.org/10.1371/journal.pone.0088667

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