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Late Multiple Organ Surge in Interferon-Regulated Target Genes Characterizes Staphylococcal Enterotoxin B Lethality
BACKGROUND: Bacterial superantigens are virulence factors that cause toxic shock syndrome. Here, the genome-wide, temporal response of mice to lethal intranasal staphylococcal enterotoxin B (SEB) challenge was investigated in six tissues. RESULTS: The earliest responses and largest number of affecte...
Autores principales: | Ferreyra, Gabriela A., Elinoff, Jason M., Demirkale, Cumhur Y., Starost, Matthew F., Buckley, Marilyn, Munson, Peter J., Krakauer, Teresa, Danner, Robert L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923834/ https://www.ncbi.nlm.nih.gov/pubmed/24551153 http://dx.doi.org/10.1371/journal.pone.0088756 |
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