Similar to Spironolactone, Oxymatrine Is Protective in Aldosterone-Induced Cardiomyocyte Injury via Inhibition of Calpain and Apoptosis-Inducing Factor Signaling

Accumulating evidence indicates that oxymatrine (OMT) possesses variously pharmacological properties, especially on the cardiovascular system. We previously demonstrated that activated calpain/apoptosis-inducing factor (AIF)-mediated pathway was the key molecular mechanism in aldosterone (ALD) induc...

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Detalles Bibliográficos
Autores principales: Xiao, Ting-Ting, Wang, Yuan-Yuan, Zhang, Yan, Bai, Cong-Hui, Shen, Xiang-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923837/
https://www.ncbi.nlm.nih.gov/pubmed/24551180
http://dx.doi.org/10.1371/journal.pone.0088856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923837/
https://www.ncbi.nlm.nih.gov/pubmed/24551180
http://dx.doi.org/10.1371/journal.pone.0088856

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