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Similar to Spironolactone, Oxymatrine Is Protective in Aldosterone-Induced Cardiomyocyte Injury via Inhibition of Calpain and Apoptosis-Inducing Factor Signaling
Accumulating evidence indicates that oxymatrine (OMT) possesses variously pharmacological properties, especially on the cardiovascular system. We previously demonstrated that activated calpain/apoptosis-inducing factor (AIF)-mediated pathway was the key molecular mechanism in aldosterone (ALD) induc...
Autores principales: | Xiao, Ting-Ting, Wang, Yuan-Yuan, Zhang, Yan, Bai, Cong-Hui, Shen, Xiang-Chun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923837/ https://www.ncbi.nlm.nih.gov/pubmed/24551180 http://dx.doi.org/10.1371/journal.pone.0088856 |
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