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WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma
Developmental and cancer models show Wnt/β-catenin-dependent signaling mediates diverse phenotypic outcomes in the pancreas that are dictated by context, duration and strength of activation. While generally assumed to be pro-tumorigenic, it is unclear to what extent dysregulation of Wnt/β-catenin si...
Autores principales: | Arensman, Michael D., Kovochich, Anne N., Kulikauskas, Rima M., Lay, Anna R., Yang, Pei-Tzu, Li, Xinmin, Donahue, Timothy, Major, Michael B., Moon, Randall T., Chien, Andy J., Dawson, David W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923845/ https://www.ncbi.nlm.nih.gov/pubmed/23416978 http://dx.doi.org/10.1038/onc.2013.23 |
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