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High-Dose Irradiation Induces Cell Cycle Arrest, Apoptosis, and Developmental Defects during Drosophila Oogenesis

Ionizing radiation (IR) treatment induces a DNA damage response, including cell cycle arrest, DNA repair, and apoptosis in metazoan somatic cells. Because little has been reported in germline cells, we performed a temporal analysis of the DNA damage response utilizing Drosophila oogenesis as a model...

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Detalles Bibliográficos
Autores principales: Shim, Hee Jin, Lee, Eun-Mi, Nguyen, Long Duy, Shim, Jaekyung, Song, Young-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923870/
https://www.ncbi.nlm.nih.gov/pubmed/24551207
http://dx.doi.org/10.1371/journal.pone.0089009