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High-Dose Irradiation Induces Cell Cycle Arrest, Apoptosis, and Developmental Defects during Drosophila Oogenesis
Ionizing radiation (IR) treatment induces a DNA damage response, including cell cycle arrest, DNA repair, and apoptosis in metazoan somatic cells. Because little has been reported in germline cells, we performed a temporal analysis of the DNA damage response utilizing Drosophila oogenesis as a model...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923870/ https://www.ncbi.nlm.nih.gov/pubmed/24551207 http://dx.doi.org/10.1371/journal.pone.0089009 |