The Expression of HIV-1 Vpu in Monocytes Causes Increased Secretion of TGF-β that Activates Profibrogenic Genes in Hepatic Stellate Cells

There is faster progression to fibrosis in persons with liver injury who are also infected with HIV. Other reports have suggested that HIV can directly infect and activate stellate cells, and the viral Tat and gp160 proteins also induce profibrogenic factors from peripheral blood mononuclear cells (...

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Detalles Bibliográficos
Autores principales: Patel, Paresh, Khan, Nabab, Rani, Manjusha, Gupta, Deepti, Jameel, Shahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923874/
https://www.ncbi.nlm.nih.gov/pubmed/24551192
http://dx.doi.org/10.1371/journal.pone.0088934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923874/
https://www.ncbi.nlm.nih.gov/pubmed/24551192
http://dx.doi.org/10.1371/journal.pone.0088934

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