Glypican-1 regulates myoblast response to HGF via Met in a lipid raft-dependent mechanism: effect on migration of skeletal muscle precursor cells

BACKGROUND: Via the hepatocyte growth factor receptor (Met), hepatocyte growth factor (HGF) exerts key roles involving skeletal muscle development and regeneration. Heparan sulfate proteoglycans (HSPGs) are critical modulators of HGF activity, but the role of specific HSPGs in HGF regulation is poor...

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Detalles Bibliográficos
Autores principales: Gutiérrez, Jaime, Cabrera, Daniel, Brandan, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923899/
https://www.ncbi.nlm.nih.gov/pubmed/24517345
http://dx.doi.org/10.1186/2044-5040-4-5

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