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An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis

Clathrin-mediated endocytosis (CME) is the major internalisation route for many different receptor types in mammalian cells. CME is shut down during early mitosis, but the mechanism of this inhibition is unclear. In this study, we show that the mitotic shutdown is due to an unmet requirement for act...

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Detalles Bibliográficos
Autores principales: Kaur, Satdip, Fielding, Andrew B, Gassner, Gisela, Carter, Nicholas J, Royle, Stephen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924242/
https://www.ncbi.nlm.nih.gov/pubmed/24550251
http://dx.doi.org/10.7554/eLife.00829