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Knee loading reduces MMP13 activity in the mouse cartilage

BACKGROUND: Moderate loads with knee loading enhance bone formation, but its effects on the maintenance of the knee are not well understood. In this study, we examined the effects of knee loading on the activity of matrix metalloproteinase13 (MMP13) and evaluated the role of p38 MAPK and Rac1 GTPase...

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Detalles Bibliográficos
Autores principales: Hamamura, Kazunori, Zhang, Ping, Zhao, Liming, Shim, Joon W, Chen, Andy, Dodge, Todd R, Wan, Qiaoqiao, Shih, Han, Na, Sungsoo, Lin, Chien-Chi, Sun, Hui Bin, Yokota, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924329/
https://www.ncbi.nlm.nih.gov/pubmed/24180431
http://dx.doi.org/10.1186/1471-2474-14-312