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Knee loading reduces MMP13 activity in the mouse cartilage
BACKGROUND: Moderate loads with knee loading enhance bone formation, but its effects on the maintenance of the knee are not well understood. In this study, we examined the effects of knee loading on the activity of matrix metalloproteinase13 (MMP13) and evaluated the role of p38 MAPK and Rac1 GTPase...
Autores principales: | Hamamura, Kazunori, Zhang, Ping, Zhao, Liming, Shim, Joon W, Chen, Andy, Dodge, Todd R, Wan, Qiaoqiao, Shih, Han, Na, Sungsoo, Lin, Chien-Chi, Sun, Hui Bin, Yokota, Hiroki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924329/ https://www.ncbi.nlm.nih.gov/pubmed/24180431 http://dx.doi.org/10.1186/1471-2474-14-312 |
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