Whole-Genome Sequencing of the Nonproteolytic Bacillus anthracis V770-NP1-R Strain Reveals Multiple Mutations in Peptidase Loci

We report the draft whole-genome sequence of the nonproteolytic Bacillus anthracis V770-NP1-R strain. Compared to those of other B. anthracis strains, the genome exhibits unique mutations in multiple targets potentially affecting proteolytic functions. One of these mutations is a deletion that disru...

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Autores principales: Cohen-Gihon, Inbar, Israeli, Ofir, Beth-Din, Adi, Levy, Haim, Cohen, Ofer, Shafferman, Avigdor, Zvi, Anat, Chitlaru, Theodor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924378/
https://www.ncbi.nlm.nih.gov/pubmed/24526646
http://dx.doi.org/10.1128/genomeA.00075-14
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author Cohen-Gihon, Inbar
Israeli, Ofir
Beth-Din, Adi
Levy, Haim
Cohen, Ofer
Shafferman, Avigdor
Zvi, Anat
Chitlaru, Theodor
author_facet Cohen-Gihon, Inbar
Israeli, Ofir
Beth-Din, Adi
Levy, Haim
Cohen, Ofer
Shafferman, Avigdor
Zvi, Anat
Chitlaru, Theodor
author_sort Cohen-Gihon, Inbar
collection PubMed
description We report the draft whole-genome sequence of the nonproteolytic Bacillus anthracis V770-NP1-R strain. Compared to those of other B. anthracis strains, the genome exhibits unique mutations in multiple targets potentially affecting proteolytic functions. One of these mutations is a deletion that disrupts the NprR quorum-sensing regulator of the NprA protease.
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spelling pubmed-39243782014-02-19 Whole-Genome Sequencing of the Nonproteolytic Bacillus anthracis V770-NP1-R Strain Reveals Multiple Mutations in Peptidase Loci Cohen-Gihon, Inbar Israeli, Ofir Beth-Din, Adi Levy, Haim Cohen, Ofer Shafferman, Avigdor Zvi, Anat Chitlaru, Theodor Genome Announc Prokaryotes We report the draft whole-genome sequence of the nonproteolytic Bacillus anthracis V770-NP1-R strain. Compared to those of other B. anthracis strains, the genome exhibits unique mutations in multiple targets potentially affecting proteolytic functions. One of these mutations is a deletion that disrupts the NprR quorum-sensing regulator of the NprA protease. American Society for Microbiology 2014-02-13 /pmc/articles/PMC3924378/ /pubmed/24526646 http://dx.doi.org/10.1128/genomeA.00075-14 Text en Copyright © 2014 Cohen-Gihon et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Prokaryotes
Cohen-Gihon, Inbar
Israeli, Ofir
Beth-Din, Adi
Levy, Haim
Cohen, Ofer
Shafferman, Avigdor
Zvi, Anat
Chitlaru, Theodor
Whole-Genome Sequencing of the Nonproteolytic Bacillus anthracis V770-NP1-R Strain Reveals Multiple Mutations in Peptidase Loci
title Whole-Genome Sequencing of the Nonproteolytic Bacillus anthracis V770-NP1-R Strain Reveals Multiple Mutations in Peptidase Loci
title_full Whole-Genome Sequencing of the Nonproteolytic Bacillus anthracis V770-NP1-R Strain Reveals Multiple Mutations in Peptidase Loci
title_fullStr Whole-Genome Sequencing of the Nonproteolytic Bacillus anthracis V770-NP1-R Strain Reveals Multiple Mutations in Peptidase Loci
title_full_unstemmed Whole-Genome Sequencing of the Nonproteolytic Bacillus anthracis V770-NP1-R Strain Reveals Multiple Mutations in Peptidase Loci
title_short Whole-Genome Sequencing of the Nonproteolytic Bacillus anthracis V770-NP1-R Strain Reveals Multiple Mutations in Peptidase Loci
title_sort whole-genome sequencing of the nonproteolytic bacillus anthracis v770-np1-r strain reveals multiple mutations in peptidase loci
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924378/
https://www.ncbi.nlm.nih.gov/pubmed/24526646
http://dx.doi.org/10.1128/genomeA.00075-14
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