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Combination of conventional immunohistochemistry and qRT-PCR to detect ALK rearrangement
BACKGROUND: Compared with FISH and qRT-PCR analyses, immunohistochemistry (IHC) is the preferred screening test in most pathology practices for ALK-rearrangement detection. With 100% sensitivity and 98% specificity, the VENTANA ALK (D5F3) IHC assay has been approved in the EU and some Asian countrie...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924409/ https://www.ncbi.nlm.nih.gov/pubmed/24422905 http://dx.doi.org/10.1186/1746-1596-9-3 |