Combination of conventional immunohistochemistry and qRT-PCR to detect ALK rearrangement

BACKGROUND: Compared with FISH and qRT-PCR analyses, immunohistochemistry (IHC) is the preferred screening test in most pathology practices for ALK-rearrangement detection. With 100% sensitivity and 98% specificity, the VENTANA ALK (D5F3) IHC assay has been approved in the EU and some Asian countrie...

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Detalles Bibliográficos
Autores principales: Shan, Ling, Lian, Fang, Guo, Lei, Yang, Xin, Ying, Jianming, Lin, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924409/
https://www.ncbi.nlm.nih.gov/pubmed/24422905
http://dx.doi.org/10.1186/1746-1596-9-3

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