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From pre-DP, post-DP, SP4, and SP8 Thymocyte Cell Counts to a Dynamical Model of Cortical and Medullary Selection
Cells of the mature αβ T cell repertoire arise from the development in the thymus of bone marrow precursors (thymocytes). αβ T cell maturation is characterized by the expression of thousands of copies of identical αβ T cell receptors and the CD4 and/or CD8 co-receptors on the surface of thymocytes....
Autores principales: | Sawicka, Maria, Stritesky, Gretta L., Reynolds, Joseph, Abourashchi, Niloufar, Lythe, Grant, Molina-París, Carmen, Hogquist, Kristin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924582/ https://www.ncbi.nlm.nih.gov/pubmed/24592261 http://dx.doi.org/10.3389/fimmu.2014.00019 |
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