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Notch1 Activation Up-Regulates Pancreatic and Duodenal Homeobox-1
Transcription factor pancreatic and duodenal homeobox-1 (PDX-1) plays an essential role in pancreatic development, β-cell differentiation, maintenance of normal β-cell function and tumorigenesis. PDX-1 expression is tightly controlled through a variety of mechanisms under different cellular contexts...
Autores principales: | Liu, Shi-He, Zhou, Guisheng, Yu, Juehua, Wu, James, Nemunaitis, John, Senzer, Neil, Dawson, David, Li, Min, Fisher, William E., Brunicardi, F. Charles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924823/ https://www.ncbi.nlm.nih.gov/pubmed/24705209 http://dx.doi.org/10.3390/genes4030358 |
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