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Antisense Gene Silencing: Therapy for Neurodegenerative Disorders?

Since the first reports that double-stranded RNAs can efficiently silence gene expression in C. elegans, the technology of RNA interference (RNAi) has been intensively exploited as an experimental tool to study gene function. With the subsequent discovery that RNAi could also be applied to mammalian...

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Detalles Bibliográficos
Autores principales: Nielsen, Troels T., Nielsen, Jørgen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924827/
https://www.ncbi.nlm.nih.gov/pubmed/24705213
http://dx.doi.org/10.3390/genes4030457