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Signaling Pathways from the Endoplasmic Reticulum and Their Roles in Disease
The endoplasmic reticulum (ER) is an organelle in which newly synthesized secretory and transmembrane proteins are assembled and folded into their correct tertiary structures. However, many of these ER proteins are misfolded as a result of various stimuli and gene mutations. The accumulation of misf...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924831/ https://www.ncbi.nlm.nih.gov/pubmed/24705207 http://dx.doi.org/10.3390/genes4030306 |