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Identification of oxidized protein hydrolase as a potential prodrug target in prostate cancer
BACKGROUND: Esterases are often overexpressed in cancer cells and can have chiral specificities different from that of the corresponding normal tissues. For this reason, ester prodrugs could be a promising approach in chemotherapy. In this study, we focused on the identification and characterization...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925015/ https://www.ncbi.nlm.nih.gov/pubmed/24512522 http://dx.doi.org/10.1186/1471-2407-14-77 |