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Therapeutic Drug Monitoring and Pharmacogenetic Study of HIV-Infected Ethnic Chinese Receiving Efavirenz-Containing Antiretroviral Therapy with or without Rifampicin-Based Anti-Tuberculous Therapy

OBJECTIVES: Plasma efavirenz concentrations in HIV-infected patients with tuberculosis (TB) may be affected by cytochrome P450 (CYP) 2B6 single-nucleotide polymorphisms and concurrent rifampicin use. We aimed to investigate the effects of CYP2B6 G516T polymorphisms and concomitant rifampicin use on...

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Detalles Bibliográficos
Autores principales:	Lee, Kuan-Yeh, Lin, Shu-Wen, Sun, Hsin-Yun, Kuo, Ching-Hua, Tsai, Mao-Song, Wu, Bing-Ru, Tang, Sue-Yo, Liu, Wen-Chun, Chang, Sui-Yuan, Hung, Chien-Ching
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925114/ https://www.ncbi.nlm.nih.gov/pubmed/24551111 http://dx.doi.org/10.1371/journal.pone.0088497

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