Cargando…

Variability in research ethics review of cluster randomized trials: a scenario-based survey in three countries

BACKGROUND: Cluster randomized trials (CRTs) present unique ethical challenges. In the absence of a uniform standard for their ethical design and conduct, problems such as variability in procedures and requirements by different research ethics committees will persist. We aimed to assess the need for...

Descripción completa

Detalles Bibliográficos
Autores principales:	Taljaard, Monica, Brehaut, Jamie C, Weijer, Charles, Boruch, Robert, Donner, Allan, Eccles, Martin P, McRae, Andrew D, Saginur, Raphael, Zwarenstein, Merrick, Grimshaw, Jeremy M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925119/ https://www.ncbi.nlm.nih.gov/pubmed/24495542 http://dx.doi.org/10.1186/1745-6215-15-48

Ejemplares similares

Ethical issues posed by cluster randomized trials in health research
por: Weijer, Charles, et al.
Publicado: (2011)

Does clinical equipoise apply to cluster randomized trials in health research?
por: Binik, Ariella, et al.
Publicado: (2011)

Ethical and policy issues in cluster randomized trials: rationale and design of a mixed methods research study
por: Taljaard, Monica, et al.
Publicado: (2009)

Who is the research subject in cluster randomized trials in health research?
por: McRae, Andrew D, et al.
Publicado: (2011)

Researchers’ perceptions of ethical challenges in cluster randomized trials: a qualitative analysis
por: McRae, Andrew D, et al.
Publicado: (2013)

What is the role and authority of gatekeepers in cluster randomized trials in health research?
por: Gallo, Antonio, et al.
Publicado: (2012)

When is informed consent required in cluster randomized trials in health research?
por: McRae, Andrew D, et al.
Publicado: (2011)

Inadequate reporting of research ethics review and informed consent in cluster randomised trials: review of random sample of published trials
por: Taljaard, Monica, et al.
Publicado: (2011)

The Ottawa Statement on the Ethical Design and Conduct of Cluster Randomized Trials
por: Weijer, Charles, et al.
Publicado: (2012)

Impact of CONSORT extension for cluster randomised trials on quality of reporting and study methodology: review of random sample of 300 trials, 2000-8
por: Ivers, N M, et al.
Publicado: (2011)

Electronic search strategies to identify reports of cluster randomized trials in MEDLINE: low precision will improve with adherence to reporting standards
por: Taljaard, Monica, et al.
Publicado: (2010)

Patient Partner Perspectives Regarding Ethically and Clinically Important Aspects of Trial Design in Pragmatic Cluster Randomized Trials for Hemodialysis
por: Nicholls, Stuart G., et al.
Publicado: (2021)

Ethical issues in pragmatic randomized controlled trials: a review of the recent literature identifies gaps in ethical argumentation
por: Goldstein, Cory E., et al.
Publicado: (2018)

The ethical challenges raised in the design and conduct of pragmatic trials: an interview study with key stakeholders
por: Nicholls, Stuart G., et al.
Publicado: (2019)

Ethical Issues in the Design and Conduct of Pragmatic Cluster Randomized Trials in Hemodialysis Care: An Interview Study With Key Stakeholders
por: Nicholls, Stuart G., et al.
Publicado: (2020)

A Scoping Review of Empirical Research Relating to Quality and Effectiveness of Research Ethics Review
por: Nicholls, Stuart G., et al.
Publicado: (2015)

Stakeholder views regarding ethical issues in the design and conduct of pragmatic trials: study protocol
por: Nicholls, Stuart G., et al.
Publicado: (2018)

Accommodating quality and service improvement research within existing ethical principles
por: Goldstein, Cory E., et al.
Publicado: (2018)

Mail merge can be used to create personalized questionnaires in complex surveys
por: Taljaard, Monica, et al.
Publicado: (2015)

Reporting of key methodological and ethical aspects of cluster trials in hemodialysis require improvement: a systematic review
por: Al-Jaishi, Ahmed A., et al.
Publicado: (2020)

Ethical implications of excessive cluster sizes in cluster randomised trials
por: Hemming, Karla, et al.
Publicado: (2018)

Informed consent in cluster randomised trials: a guide for the perplexed
por: Nix, Hayden P, et al.
Publicado: (2021)

Delayed educational reminders for long-term medication adherence in ST-elevation myocardial infarction (DERLA-STEMI): Protocol for a pragmatic, cluster-randomized controlled trial
por: Ivers, Noah M, et al.
Publicado: (2012)

When and how should we cluster and cross over: methodological and ethical issues
por: Goldstein, Cory E., et al.
Publicado: (2018)

Educational outreach to general practitioners reduces children's asthma symptoms: a cluster randomised controlled trial
por: Zwarenstein, Merrick, et al.
Publicado: (2007)

Heterogeneity in pragmatic randomised trials: sources and management
por: Giraudeau, Bruno, et al.
Publicado: (2022)

Developing a framework for the ethical design and conduct of pragmatic trials in healthcare: a mixed methods research protocol
por: Taljaard, Monica, et al.
Publicado: (2018)

Theory of planned behaviour can help understand processes underlying the use of two emergency medicine diagnostic imaging rules
por: Perez, Richard, et al.
Publicado: (2014)

Commentary: Ethics in conduct of trials in developing countries
por: Weijer, Charles
Publicado: (2010)

TwiC or treat? Are trials within cohorts ethically defensible?
por: Weijer, Charles, et al.
Publicado: (2017)

Introducing the new CONSORT extension for stepped-wedge cluster randomised trials
por: Hemming, Karla, et al.
Publicado: (2019)

Allocation techniques for balance at baseline in cluster randomized trials: a methodological review
por: Ivers, Noah M, et al.
Publicado: (2012)

Using theories of behaviour to understand transfusion prescribing in three clinical contexts in two countries: Development work for an implementation trial
por: Francis, Jill J, et al.
Publicado: (2009)

Ethical issues in implementation research: a discussion of the problems in achieving informed consent
por: Hutton, Jane L, et al.
Publicado: (2008)

Requirements for ethics committee review for studies submitted to Implementation Science
por: Eccles, Martin P, et al.
Publicado: (2011)

Changing patient preferences toward better trial recruitment: an ethical analysis
por: Al, Pepijn, et al.
Publicado: (2023)

Can patient decision aids help people make good decisions about participating in clinical trials? A study protocol
por: Brehaut, Jamie C, et al.
Publicado: (2008)

Response to Merz
por: Al, Pepijn, et al.
Publicado: (2023)

Feedback GAP: study protocol for a cluster-randomized trial of goal setting and action plans to increase the effectiveness of audit and feedback interventions in primary care
por: Ivers, Noah M, et al.
Publicado: (2010)

A cross-country comparison of intensive care physicians’ beliefs about their transfusion behaviour: A qualitative study using the theoretical domains framework
por: Islam, Rafat, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_2b341ta2q34a32uinmgdepvpap