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The Pestivirus N Terminal Protease N(pro) Redistributes to Mitochondria and Peroxisomes Suggesting New Sites for Regulation of IRF3 by N(pro)
The N-terminal protease of pestiviruses, N(pro) is a unique viral protein, both because it is a distinct autoprotease that cleaves itself from the following polyprotein chain, and also because it binds and inactivates IRF3, a central regulator of interferon production. An important question remains...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925175/ https://www.ncbi.nlm.nih.gov/pubmed/24551175 http://dx.doi.org/10.1371/journal.pone.0088838 |