Cargando…

GLA-AF, an Emulsion-Free Vaccine Adjuvant for Pandemic Influenza

The ongoing threat from Influenza necessitates the development of new vaccine and adjuvant technologies that can maximize vaccine immunogenicity, shorten production cycles, and increase global vaccine supply. Currently, the most successful adjuvants for Influenza vaccines are squalene-based oil-in-w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Clegg, Christopher H., Roque, Richard, Perrone, Lucy A., Rininger, Joseph A., Bowen, Richard, Reed, Steven G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925208/ https://www.ncbi.nlm.nih.gov/pubmed/24551202 http://dx.doi.org/10.1371/journal.pone.0088979

Ejemplares similares

The adjuvant GLA-AF enhances human intradermal vaccine responses
por: Carter, Darrick, et al.
Publicado: (2018)

Adjuvanted pandemic influenza vaccine: variation of emulsion components affects stability, antigen structure, and vaccine efficacy
por: Fox, Christopher B., et al.
Publicado: (2012)

Preparedness against pandemic influenza: Production of an oil-in-water emulsion adjuvant in Brazil
por: Akamatsu, Milena Apetito, et al.
Publicado: (2020)

The TLR4 Agonist Vaccine Adjuvant, GLA-SE, Requires Canonical and Atypical Mechanisms of Action for T(H)1 Induction
por: Cauwelaert, Natasha Dubois, et al.
Publicado: (2016)

A Synthetic Adjuvant to Enhance and Expand Immune Responses to Influenza Vaccines
por: Coler, Rhea N., et al.
Publicado: (2010)

Glucopyranosyl Lipid Adjuvant (GLA), a Synthetic TLR4 Agonist, Promotes Potent Systemic and Mucosal Responses to Intranasal Immunization with HIVgp140
por: Arias, Mauricio A., et al.
Publicado: (2012)

Global Mortality Estimates for the 2009 Influenza Pandemic from the GLaMOR Project: A Modeling Study
por: Simonsen, Lone, et al.
Publicado: (2013)

The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes
por: Hill, Danika L., et al.
Publicado: (2019)

The TLR-4 agonist adjuvant, GLA-SE, improves magnitude and quality of immune responses elicited by the ID93 tuberculosis vaccine: first-in-human trial
por: Coler, Rhea N., et al.
Publicado: (2018)

Evolution of Matrix Gla and Bone Gla Protein Genes in Jawed Vertebrates
por: Leurs, Nicolas, et al.
Publicado: (2021)

Oil-in-water emulsion adjuvants for pediatric influenza vaccines: a systematic review and meta-analysis
por: Lin, Yu-Ju, et al.
Publicado: (2020)

“World in motion” – emulsion adjuvants rising to meet the pandemic challenges
por: O’Hagan, Derek T., et al.
Publicado: (2021)

Telehealth delivery of GLA:D® Australia during the COVID-19 pandemic
por: Barton, C., et al.
Publicado: (2021)

A Formulated TLR7/8 Agonist is a Flexible, Highly Potent and Effective Adjuvant for Pandemic Influenza Vaccines
por: Van Hoeven, Neal, et al.
Publicado: (2017)

From mouse to man: safety, immunogenicity and efficacy of a candidate leishmaniasis vaccine LEISH-F3+GLA-SE
por: Coler, Rhea N, et al.
Publicado: (2015)

Author Correction: “World in motion” – emulsion adjuvants rising to meet the pandemic challenges
por: O’Hagan, Derek T., et al.
Publicado: (2023)

Matrix Gla protein in tumoral pathology
por: GHEORGHE, SIMONA ROXANA, et al.
Publicado: (2016)

Development of the Brazilian Anti Schistosomiasis Vaccine Based on the Recombinant Fatty Acid Binding Protein Sm14 Plus GLA-SE Adjuvant
por: Tendler, Miriam, et al.
Publicado: (2015)

Adjuvanted influenza vaccine dynamics
por: Parra-Rojas, César, et al.
Publicado: (2019)

MF59(®)‐adjuvanted vaccines for seasonal and pandemic influenza prophylaxis
por: Banzhoff, Angelika, et al.
Publicado: (2008)

Development of a novel oil-in-water emulsion and evaluation of its potential adjuvant function in a swine influenza vaccine in mice
por: Zhang, Jinqiu, et al.
Publicado: (2018)

Global mortality associated with seasonal influenza epidemics: New burden estimates and predictors from the GLaMOR Project
por: Paget, John, et al.
Publicado: (2019)

Alum Pickering Emulsion as Effective Adjuvant to Improve Malaria Vaccine Efficacy
por: Chen, Qiuting, et al.
Publicado: (2021)

Mixing Time, Inversion and Multiple Emulsion Formation in a Limonene and Water Pickering Emulsion
por: Sawiak, Laura, et al.
Publicado: (2018)

THE USE OF ADJUVANTS IN STUDIES ON INFLUENZA IMMUNIZATION : I. MEASUREMENTS IN MONKEYS OF THE DIMENSIONS OF ANTIGENICITY OF VIRUS-MINERAL OIL EMULSIONS
por: Salk, Jonas E., et al.
Publicado: (1952)

Pandemic influenza vaccine: characterization of A/California/07/2009 (H1N1) recombinant hemagglutinin protein and insights into H1N1 antigen stability
por: Feshchenko, Elena, et al.
Publicado: (2012)

Protective effect of single‐dose adjuvanted pandemic influenza vaccine in children
por: Van Buynder, P. G., et al.
Publicado: (2010)

Advances in Adjuvanted Influenza Vaccines
por: Shichinohe, Shintaro, et al.
Publicado: (2023)

The effect of Pickering emulsion adjuvants on the immune efficacy of the COVID-19 polypeptide vaccine
por: Huang, Zhuanqing, et al.
Publicado: (2023)

The feasibility of implementing an English language version of GLA:D Back
por: Lemieux, J., et al.
Publicado: (2021)

Frequent Anti-V1V2 Responses Induced by HIV-DNA Followed by HIV-MVA with or without CN54rgp140/GLA-AF in Healthy African Volunteers
por: Msafiri, Frank, et al.
Publicado: (2020)

The potential consequences of bidirectional promoter methylation on GLA and HNRNPH2 expression in Fabry disease phenotypes in a family of patients carrying a GLA deletion variant
por: Al-Obaide, Mohammed A., et al.
Publicado: (2022)

Enantioselective sulfoxidation using Streptomyces glaucescens GLA.0
por: Salama, Sara, et al.
Publicado: (2020)

Phenotypes of undiagnosed adults with actionable OTC and GLA variants
por: Gold, Jessica I., et al.
Publicado: (2023)

Effectiveness of Non-Adjuvanted Pandemic Influenza A Vaccines for Preventing Pandemic Influenza Acute Respiratory Illness Visits in 4 U.S. Communities
por: Griffin, Marie R., et al.
Publicado: (2011)

AFS Monitoring: The CERN AFS Console
por: Wiebalck, Arne
Publicado: (2008)

Degradable emulsion as vaccine adjuvant reshapes antigen-specific immunity and thereby ameliorates vaccine efficacy
por: Huang, Chung-Hsiung, et al.
Publicado: (2016)

Aluminum salts as an adjuvant for pre-pandemic influenza vaccines: a meta-analysis
por: Lin, Yu-Ju, et al.
Publicado: (2018)

Influenza symptoms and their impact on elderly adults: randomised trial of AS03-adjuvanted or non-adjuvanted inactivated trivalent seasonal influenza vaccines
por: van Essen, Gerrit A, et al.
Publicado: (2014)

Construction of an enantiopure bivalent nicotine vaccine using synthetic peptides
por: Zeigler, David F., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_sk69g363ek88uqdbnrk6pct91h