Filamin B Regulates Chondrocyte Proliferation and Differentiation through Cdk1 Signaling

Humans who harbor loss of function mutations in the actin-associated filamin B (FLNB) gene develop spondylocarpotarsal syndrome (SCT), a disorder characterized by dwarfism (delayed bone formation) and premature fusion of the vertebral, carpal and tarsal bones (premature differentiation). To better u...

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Detalles Bibliográficos
Autores principales: Hu, Jianjun, Lu, Jie, Lian, Gewei, Zhang, Jingping, Hecht, Jonathan L., Sheen, Volney L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925234/
https://www.ncbi.nlm.nih.gov/pubmed/24551245
http://dx.doi.org/10.1371/journal.pone.0089352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925234/
https://www.ncbi.nlm.nih.gov/pubmed/24551245
http://dx.doi.org/10.1371/journal.pone.0089352

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